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Drugs such as nitroglycerin have been used to relieve angina, as the slow release of NO upon degradation of nitroglycerin causes increased cGMP, resulting in reduced myocardial wall tension, dilation of epicardial coronary vessels, and increased blood flow in collateral vessels

Thus, maintenance of balanced ROS production with antioxidant activity is critical for cell viability

To check for any serious skin conditions, they might also perform a biopsy but it is usually not performed these days because other non-invasive modalities such as dermatoscopy are available

Determination of uric acid concentration includes phosphotungistic acid methods (PTA), uricase methods (in wide usage), high-performance liquid chromatography methods (reference methods), dry chemistry systems (12) and biosensor methods (85)